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(R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride

(R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride - CAS 39637-99-5

(R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride is a chiral resolution reagent to separate racemic compounds into different mirror isomers and is an important tool for the production of optically active drugs.

Catalog Number

39637-99-5

CAS

39637-99-5

IUPAC Name

(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride

Synonyms

(-)-Mosher's Acid Chloride (ca. 18% in Dichloromethane, ca. 1.0mol/L),(R)-(-)-MTPA-Cl (ca. 18% in Dichloromethane, ca. 1.0mol/L)

Molecular Weight

252.618

Molecular Formula

C10H8ClF3O2

Product Information

Canonical SMILES

CO[[email protected]@](C1=CC=CC=C1)(C(=O)Cl)C(F)(F)F

InChI

InChI=1S/C10H8ClF3O2/c1-16-9(8(11)15,10(12,13)14)7-5-3-2-4-6-7/h2-6H,1H3/t9-/m0/s1

InChI Key

PAORVUMOXXAMPL-VIFPVBQESA-N

MDL

MFCD00044400

Formulation

1M in dichloromethane

Physical State

Liquid

Storage

Sealed in dry. Inert atmosphere. -20 ℃.

Boiling Point

213-214 ℃ / 760 mmHg

Flash Point

89 °C(192 °F)

Density

1.353 g/mL

Optical Activity

-137°±2°(c = 6.4 in carbon tetrachloride); -137°(c = neat); -148.5°±3.5°(c = 2 in toluene); -132°±2°(c = 6 in chloroform)

Solubility

Reacts with water.

Refractive Index

1.47

Hazard Class

TSCA

WGK Germany

Packing Groups

Safety Information

Signal Word

Danger

Precautionary Statement

P210 - P235 - P260 - P264b - P271 - P280 - P301+P330+P331 - P303+P361+P353 - P304+P340 - P305+P351+P338 - P310 - P363 - P370+P378q - P501c

Hazard Statements

H314

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(R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride - CAS 39637-99-5

Product Information

Safety Information

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