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(R)-α,α-bis[3,5-bis-(Trifluoromethyl)phenyl]-2-pyrrolidinemethanol

(R)-α,α-bis[3,5-bis-(Trifluoromethyl)phenyl]-2-pyrrolidinemethanol - CAS 948595-00-4

(R)-α,α-bis[3,5-bis-(Trifluoromethyl)phenyl]-2-pyrrolidinemethanol is a proline-based organocatalyst that has been investigated for several powerful asymmetric transformations, such as the Aldol, Mannich, and Michael reactions.

Catalog Number

948595-00-4

CAS

948595-00-4

IUPAC Name

bis[3,5-bis(trifluoromethyl)phenyl]-[(2R)-pyrrolidin-2-yl]methanol

Synonyms

(R)-2-{Bis[3,5-bis(trifluoromethyl)phenyl]hydroxymethyl}pyrrolidine

Molecular Weight

525.33

Molecular Formula

C21H15F12NO

Product Information

Canonical SMILES

OC([C@H]1CCCN1)(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cc(cc(c3)C(F)(F)F)C(F)(F)F

InChI

InChI=1S/C21H15F12NO/c22-18(23,24)12-4-10(5-13(8-12)19(25,26)27)17(35,16-2-1-3-34-16)11-6-14(20(28,29)30)9-15(7-11)21(31,32)33/h4-9,16,34-35H,1-3H2/t16-/m1/s1

InChI Key

ITXPGQOGEYWAKW-MRXNPFEDSA-N

Purity

≥99%

MDL

MFCD10566975

Physical State

Solid

Storage

Keep cold.

Melting Point

113-117 °C