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(R)-α,α-bis[3,5-bis-(Trifluoromethyl)phenyl]prolinol trimethylsilyl ether

(R)-α,α-bis[3,5-bis-(Trifluoromethyl)phenyl]prolinol trimethylsilyl ether - CAS 908303-26-4

(R)-α,α-bis[3,5-bis-(Trifluoromethyl)phenyl]prolinol trimethylsilyl ether is a proline-based organocatalyst that has been investigated for several powerful asymmetric transformations, such as the Aldol, Mannich, and Michael reactions.

Catalog Number

908303-26-4

CAS

908303-26-4

IUPAC Name

[bis[3,5-bis(trifluoromethyl)phenyl]-[(2R)-pyrrolidin-2-yl]methoxy]-trimethylsilane

Synonyms

(R)-alpha,alpha-bis[3,5-bis-(Trifluoromethyl)phenyl]prolinol trimethylsilyl ether; (2R)-2-[Bis[3,5-bis(trifluoromethyl)phenyl][(trimethylsilyl)oxy]methyl]pyrrolidine

Molecular Weight

597.51

Molecular Formula

C24H23F12NOSi

Product Information

Canonical SMILES

C[Si](C)(C)OC([C@H]1CCCN1)(c2cc(cc(c2)C(F)(F)F)C(F)(F)F)c3cc(cc(c3)C(F)(F)F)C(F)(F)F

InChI

InChI=1S/C24H23F12NOSi/c1-39(2,3)38-20(19-5-4-6-37-19,13-7-15(21(25,26)27)11-16(8-13)22(28,29)30)14-9-17(23(31,32)33)12-18(10-14)24(34,35)36/h7-12,19,37H,4-6H2,1-3H3/t19-/m1/s1

InChI Key

MOHRGTBNEJKFMB-LJQANCHMSA-N

MDL

MFCD09750448

Physical State

Solid

Storage

-20 °C.

Melting Point

46-55 °C

Flash Point

> 110 °C(230.0 °F)

WGK Germany

Safety Information

Signal Word

Warning

Precautionary Statement

P302+P352 - P305+P351+P338

Hazard Statements

H315 - H319 - H335

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(R)-α,α-bis[3,5-bis-(Trifluoromethyl)phenyl]prolinol trimethylsilyl ether - CAS 908303-26-4

Product Information

Safety Information

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